Provisional Programme



12:00 pm                               Registration starts

12:00 pm -1:00 pm                         Lunch

Session 1: Meiotic Recombination and Repair

1:00 pm                     Stephen Gray

MRC Genome Damage and Stability Centre, University of Sussex.

“Ectopic/non-allelic homologous recombination occurs in a checkpoint defective, recombinase-independent manner”

1:20 pm                     Emad Ahmed

Zoology department, Assiut University; Department of Molecular Biology and Biotechnology, University of Sheffield

“ NHEJ repair in testicular cells and at meiotic telomeres of pachytene spermatocytes”

1:40 pm                     James Crichton

Institute of Genetics and Molecular Medicine, MRC Human Genetics Unit, University of Edinburgh

“Germline genome defence mutations cause meiotic chromosome asynapsis through altered chromosome structure and defective initiation of recombination”

2:00 pm                     Ye Hong

Centre for Gene Regulation and Expression, University of Dundee

“Combinational regulation of meiotic recombination intermediated metabolism and chiasma formation by SMC-5/6 complex and HIM-6(BLM) helicase in C. elegans

2:20 pm                     Ta-Chung Chou

Department of Molecular Biology and Biotechnology, University of Sheffield

“ The molecular role of the Saccharomyces cerevisiae DNA helicase Srs2 during meiotic recombination”

2:40 pm                     Nicola Silva

MRC, Clinical Science Centre, London

“ Prolyl aminopeptidase APP-1/XPNPEP1 prevents the accumulation of DNA damage by restricting Topoisomerase II levels”.

3:00 pm                                 Tea break and poster viewing


Session 2: Meiotic spindles and kinetochores [sponsored by Digital Scientific UK]

3:30 pm                     Nadine Vincenten

Wellcome Trust Centre for Cell Biology, University of Edinburgh

The Ctf19 kinetochore complex ensures faithful segregation of homologous chromosomes in meiosis I”.

3:50 pm                     Sara Carvalhal

Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee

“ALADIN, a tale of two divisions – ALADIN is required for proper mitotic and meiotic spindle formation”.

4.10 pm                     Dean Clift

MRC Laboratory of Molecular Biology, Cambridge

“MTOC fragmentation safeguards bipolar spindle assembly in mouse oocytes”

4.30 pm                     Aicha Metchat

European Molecular Biology Laboratory (EMBL), Cell Biology and Biophysic Unit; Institute of Ageing and Health, Center of life, Newcastle University

“A spindle position checkpoint ensures the asymmetric division in mammalian oocytes”

4.50 pm                     Katja Wassmann (Guest speaker)

IBPS, UPMC-UMR7622, Group Cell Division and Associated Checkpoints, 75005 Paris

“How oocytes try to get it right: Spindle checkpoint control in meiosis I”

5:30 pm                     Poster session

7:00 pm                     Dinner



Session 3: Chromosome structure and axes  [Sponsored by Formedium]  

9:00 am                     Christophe Lambing

University of Birmingham

“Coordinated chromosome axis remodeling by PCH2 is essential for CO assurance and interference in plants”

9:20 am                     Elvira Nikalayevich

Wellcome Trust Centre for Cell Biology, University of Edinburgh

“Chromatin-remodelling complex NuRD and histone kinase NHK-1 are required for chromosome condensation in Drosophila oocytes”.

9:40 am                     Johanna Syrjanen

Department of Biochemistry, University of Cambridge

“The crystal structure of human synaptomenal complex protein SYCP3 and implications for its role in meiosis”

10:00 am                   Franz Klein (Guest speaker)

Chromosome Biology, Max F. Perutz Laboratories, University of Vienna

Smc5/6-Mms21 antagonizes Joint Molecules by two separable mechanisms”

10:40 am                   Tea break and poster viewing


Session 4: Crossover control

11:10 am                   Abdellah Barakate

Division of Plant Sciences, University of Dundee at The James Hutton Institute

“Manipulation of crossovers in barley (Hordeum vulgare)”

11:30 am                   Amritpal Sandhu

The School of Biosciences, University of Birmingham

Can we use the chromatin modifying chemical trichostatin A to influence crossover distribution and frequency in barley?

11:50 am                   Piotr Ziolkowski

Department of Plant Sciences, University of Cambridge; 2Department of Biotechnology, Adam Mickiewicz University, Poznan, Poland

“Meiotic crossover is driven to heterozygous regions in Arabodopsis thaliana

12:10 pm                   Poster/talk prize presentation and closing remarks

12:20 pm                   Lunch